The JSOW is a standoff weapon that is available on a number of American aircraft including the F/A-18C and soon it will be on the DCS: F-16C. A pair of videos from Eagle Dynamics Matt Wagner covers employment of the weapon system and some of the use cases for it.
The USAF uses only the AGM-154A submunition dispenser variant of the glide bomb. The weapon will reach its target and then release 145 BLU-97/B Combined Effects Bomb (CEB) which will scatter over the target zone.
In the first video, Matt Wagner covers the how-to of using the JSOW on the F-16.
The second video is also very interesting because it covers the way in which the weapon is used. In his example, Matt talks about using the weapon for DEAD (destruction of enemy air defenses). The spread of the submunitions across the targeted area is very useful at knocking out several components of the often spread out SAM sites.
This weapon is likely to come to the F-16 in the next significant update to the DCS World open beta.